A healthcare staff of Tamenglong district hospital was found positive for Coronavirus on Saturday.
One COVID-19 positive from Churachandpur is a returnee while four are from Imphal with two military personnel and eight locals of the district.
Mizoram remains one of the least COVID-19 affected states in the country.
The state recorded 254 new COVID-19 positive cases on Friday.
A total of 6,74,36,031 samples have been tested as of September 23, the ICMR states.